Mentrik Biotech Careers in Dallas, TX

Mentrik Biotech, LLC is a private biopharmaceutical company headquartered in Dallas, TX. The goal of Mentrik Biotech is to optimize oncology-based therapeutics to treat patients with significant unmet medical needs. The company aims to develop convenient, potent, and cost-effective anti-cancer molecules to enhance treatment options for patients and fulfill unmet therapeutic needs. Mentrik is developing ocaratuzumab (AME-133v), a humanized, next-generation anti-CD20 monoclonal antibody. It is engineered for enhanced affinity to CD20 and increased antibody-dependent cell-mediated cytotoxicity (ADCC), and is designed for improved treatment for low-affinity FcγRIIIa allotypes. Phase I/II trials in follicular lymphoma have been conducted in the US and Japan, and a Phase I trial in US rheumatoid arthritis patients. Continued Phase III development in relapsed follicular lymphoma patients is underway. Many patients relapse following current available treatments and a significant need for new